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王开发




基本信息

   

姓名:王开发


籍贯:四川绵竹


民族:汉族


职称:教授


所在部门(教研室):微分方程教研室


办公室:星际电子在线701


电子邮件:kfwang72@163.com






教育背景


1990.09-1994.07 星际电子在线数学系、数学教育专业、学士

1994.09-1997.07 星际电子在线数学系、基础数学专业、硕士

2004.09-2007.07 西南老员工命科学学院、生态学专业数员工态学方向、博士

2008.11-2009.10 美国亚利桑那州立大学数学系、访问学者




工作经历


2018.10-今 星际电子在线|中国有限公司官网,教授




研究领域


主要从事生物数学、生物统计与计算医学方面的研究,包括病毒感染动力学机理、临床数据分析和传染病建模。




主讲课程


《常微分方程》、《高等数学》、《生物医学统计》





学术兼职


[1] 重庆数学学会,常务理事

[2] 中国工业与应用数学学会医药数学专业委员会,常务理事

[3] 中国数学会生物数学专业委员会,常务委员

[4] 生物数学学报,常务编委

[5] Burns & Trauma, Statistical Editor

[6] 国家自然科学基金,通讯评议专家

[7] 美国《Mathematical Review》,评论员




代表性项目


[1] 国家自然科学基金面上项目,慢性乙型肝炎功能性治愈的群体动力学模型研究,No. 12171396,2022.01-2025.12,51.00 万

[2] 国家自然科学基金面上项目,乙型肝炎病毒共价闭合环状 DNA 群体动力学研究,No. 11771448,2018.01-2021.12,48.00 万

[3] 国家自然科学基金面上项目,宿主体内乙型肝炎病毒群体动力学模型研究,No. 11271369,2013.01-2016.12,65.00 万

[4] 国家自然科学基金面上项目,乙型肝炎病毒动力学模型的时-空效应分析,No. 30770555,2008.01-2010.12,23.00 万

[5] 国家自然科学基金青年项目,抗生素与活菌对微生态平衡影响的数学模型研究,No. 10101029,2002.01-2003.12,5.00 万




代表性论文


[1] Qian Zhang, Xiaoxiao Liu, Qiang Li, Yushuang Liu, Hongbo He, Kaifa Wang*, Zhencheng Yan*. Quantitative model for assessment of lower-extremity perfusion in patients with diabetes. Medical Physics,  2023; 1-8. DOI: 10.1002/mp.16214.

[2] Xiang Sun, Chenxi Dai, Kai Wang, Yuanbao Liu, Xinye Jin, Congyue Wang, Yi Yin, Zhongxing Ding, Zhenzhen Lu, Weiming Wang, Zhiguo Wang, Fenyang Tang*, Kaifa Wang*, Zhihang Peng*. A Dynamic compartmental model to explore the optimal strategy of varicella vaccination: an epidemiological study in Jiangsu Province, China. Tropical Medicine and Infectious Disease. 2023, 8, 17. DOI: 10.3390/tropicalmed8010017.

[3] Yi Hu, Kaifa Wang, Wendi Wang*. Analysis of the geographic transmission differences of COVID-19 in China caused by population movement and population density. Bulletin of Mathematical Biology, (2022) 84: 94. DOI: 10.1007/s11538-022-01050-2.

[4] Haonan Zhong, Kaifa Wang, Wendi Wang*. Spatiotemporal pattern recognition and dynamical analysis of COVID-19 in Shanghai, China. Journal of Theoretical Biology, 2022, 554: 111279. DOI: 10.1016/j.jtbi.2022.111279.

[5] Chenxi Dai, Kaifa Wang*. Adaptive weighted neighbors method for sensitivity analysis. Interdisciplinary Sciences: Computational Life Sciences, 2022, 14: 652-668. DOI: 10.1007/s12539-022-00512-4.

[6] Jiang Long, Chenxi Dai, Shanshan Kuang, Han Zhao, Dan Liu, Qing Luo, Kaifa Wang*. A switching dynamic model based on phased COVID-19 data in Chongqing and its evaluation. Infection, Genetics and Evolution, 2022, 100: 105270. DOI: 10.1016/j.meegid.2022.105270.

[7] Wencai Qi, Yuming Wang, Guangyu Huang*, Kaifa Wang*. Interleukin‐2 promotes pegylated interferon alpha for hepatitis B surface antigen loss: A retrospective pragmatic clinical study at the Fourth Affiliated Hospital of Zhejiang University Medical College. Health Science Report, 2022, 5: e932. DOI: 10.1002/hsr2.93.

[8] Cuicui Jiang, Huan Kong, Guohong Zhang*, Kaifa Wang*. Global properties of a virus dynamics model with self-proliferation of CTLs. Mathematics in Applied Sciences and Engineering, 2021, 2(2): 123-133. DOI: 10.5206/mase/13822.

[9] Chenxi Dai1, Jing Yang,Kaifa Wang*. Evaluation of prevention and control interventions and its impact on the epidemic of coronavirus disease 2019 in Chongqing and Guizhou Provinces. Mathematical Biosciences and Engineering, 2020, 17(4): 2781-2791. DOI: 10.3934/mbe.2020152.

[10] Yang Kuang*, Kaifa Wang*. Coexistence and extinction in a data-based ratio-dependent model of an insect community. Mathematical Biosciences and Engineering, 2020, 17(4): 3274-3293. DOI: 10.3934/mbe.2020187.

[11] Huan Kong, Guohong Zhang*, Kaifa Wang*. Stability and Hopf bifurcation in a virus model with self-proliferation and delayed activation of immune cells. Mathematical Biosciences and Engineering, 2020, 17(5): 4384-4405. DOI: 10.3934/mbe.2020242.

[12] 胡義,王开发,王稳地*. 2019新型冠状病毒肺炎疫情传播能力及疫情控制效能的地域差异分析. 应用数学学报,2020, 43(2): 227-237.

[13] Qiang Li, Furong Lu, Chenxi Dai, Mingjun Fan, Weiming Wang, Kaifa Wang*. Simulating the potential role of media coverage and infected bats in the 2014 Ebola outbreak. Journal of Theoretical Biology, 2017, 412: 123-129.

[14] Lijuan Song, Cui Ma, Qiang Li, Aijun Fan, Kaifa Wang*. Global dynamics of a viral infection model with full logistic terms and antivirus treatments. International Journal of Biomathematics, 2017, 10(1): 1750012, p. 24. DOI: 10.1142/S1793524517500127.

[15] Cuicui Jiang, Kaifa Wang*, Lijuan Song. Global dynamics of a delay virus model with recruitment and saturation effects of immune responses. Mathematical Biosciences and Engineering, 2017, 4: 1233-1246.

[16] Huaqiao Zhang, Hong Chen, Cuicui Jiang, Kaifa Wang*. Effect of explicit dynamics of free virus and intracellular delay. Chaos, Solitons and Fractals, 2017, 104: 827–834.

[17] Qiang Li, Furong Lu, Guohong Deng*, Kaifa Wang*. Modeling the effects of covalently closed circular DNA and dendritic cells in chronic HBV infection. Journal of Theoretical Biology, 2014, 357: 1-9.

[18] Kaifa Wang, Yu Jin*, Aijun Fan. The effect of immune responses in viral infections: a mathematical model view. Discrete and Continuous Dynamical Systems-Series B, 2014, 19(10): 3379-3396.

[19] Xi Peng#, Kaifa Wang#, Yong Zhang, Hong Yan, Chao Wang, Lijuan Song, Hongyu Wang, Dan Wu, Hua Jiang, Shiliang Wang. Establishment and Assessment of New Formulas for Energy Consumption Estimation in Adult Burn Patients. PLoS ONE, 2014, 9(10): e110409. doi:10.1371/journal.pone.0110409.

[20] Qiang Li, Furong Lu, Kaifa Wang*. Modeling of HIV-1 infection: insights to the role of monocytes/macrophages, latently infected T4 cells, and HAART regimes. PLoS ONE, 2012, 7(9): e46026. doi:10.1371/journal.pone.0046026.(Faculty of 1000 医学推荐)




代表性获奖


[1] 中国人民解放军科学技术进步奖三等奖(微生态系统数学建模系列研究,1/4),2003 年,总后勤部

[2] 军队优秀专业技术人才三类岗位津贴,2011 年,总后勤部

[3] 中国发明专利(一种符合烧伤患者代谢特点的能量消耗估算方法,CN201410425692.4.,2/5),2014年,中国

[4] 重庆市科技进步一等奖(烧伤后肠道损伤引发高代谢的机制及防治策略, 重庆市人民政府,8/10),2019年,重庆市人民政府